What is a high blood Creep Rate (LED) and what is the cause?

Surely you ever accidentally checked the blood and found the results based on the value of the reference laboratory of the State where you have a high blood creep rate. The rate of blood or creep in English is called the Erythrocyte Sedimentation Rate (ESR) is the speed required by the red blood cells to settle in a test tube with the units mm/h under the influence of gravity. The history of this LED test was first discovered in 1987 by a doctor from Poland named Edmund Faustyn Biernacki.

The LED test is carried out using two methods of examination i.e. Westergen Wintrobe method and method, but in its development the International Commitee for Standardization in Hematology (ICSH) prefers the use of methods Westergen because have a more convincing results. But what is the meaning of clinical examination of this blood creep rate and what are the causes of high blood creep rate? Let us refer to the explanation below.

What is the meaning of Clinical Blood Creep Rate high?
High blood creep rate will certainly make you worry even if you don't know the meaning of the results of the examination. Based on the value of reference examination LED by using the method of normal reference Westergen is 0-10 mm/hour for men and 0-15 mm/day for women. A number of studies find that the basic factors that affect blood creep rate of examination is the levels of fibrinogen of blood.

Fibrinogen is one protein produced in the liver and plays an important role in the process of blood clotting. Examination LED actually is one of the laboratory examination of blood which is often done for reasons practical and cheap, but its use less imputed because results indicated less specific to a disease and strongly influenced by the variety of conditions in the human body.

The conclusion that can be drawn a clinicians if it finds high blood creep rate by observing a patient complaints is the presence of an acute or chronic inflammation processes, the presence of a degenerative process (decreased organ function) or a process of cell death in the body of the person. But need to be reminded again that the blood creep rate is not a specific response from an illness and also damage cells in the body, then you need to pay attention to some of the conditions that can affect changes this LED inspection results that will We discuss next.

Factors Cause High Blood Creep Rate
After we see the clinical significance of examination of blood creep rate is indeed not so specific, now you need to figure out a number of factors which play a role in influencing the outcome of the inspection as it can increase the value of blood creep rate.

Old age
Factors cause high blood creep rate first we discuss is the age. On old age blood creep rate of one becomes higher, the rate of assessment of the reference creep this evening at the age of blood also changes. A man with age above 50 years LED a normal reference is in the range of 0-20 mm/h, whereas in women aged over 50 years of reference used is 0-30 mm/hour.

Pregnant women
Factors cause high blood creep rate of next is a condition experienced by pregnant women. In pregnant women often encountered LED inspection results are high, this is caused by a number of things. The first, as already mentioned previously LED inspection results closely related to levels of fibrinogen in the blood. In pregnant women increase the production of fibrinogen, moreover in pregnant women, there is an increase in the volume of fluid in the blood vessels so that blood creep rate becomes higher.

Anemia disease
The disease anemia or less blood is often associated with high blood creep rate. This is caused by a comparison of the number of red blood cells that are less compared to the plasma fluid in the blood vessels, and the condition causing the speed of the flow of red blood cells increases.  In addition, an anemic condition makrositik where the size of the red blood cells become larger can also increase blood creep rate.

Infection
The next cause is high blood creep rate of infectious diseases that occur in the body. Blood creep rate is often used as a blood lab tests in order to check the acute phase reactant, a substance in the blood that will increase in response to infection, trauma, damage the body's cells, a number of cancer, burns and even in response to an operation
LED examination against the conditions above still is one of the best vetting is done, but a number of studies state that examination LED is a test that can illustrate the acute phase response of a disease After the first 24 hours. For it during the first 24 hours of acute phase response recommended an examination of other better i.e. inspection of C-reactive protein. It's just an examination of C-reactive protein is more expensive and takes longer compared to the LED's examination.

The process of inflammation
High blood creep rate can also be found in the process of inflammation (inflammatory) that occur within the human body any good cause infection and infection. This is caused by an inflammatory response in which the body will increase the formation of fibrinogen and resulted in an increase in the rate of blood creep.

Technical factors
In addition to a number of health conditions mentioned above, technical factors can also be a cause of high blood creep rate. Some of these factors, among others, related to the issue of dilution, the increase in the temperature of the material inspection and also miringnya tube used on examination of blood creep rate. For that is the result of the examination of these LEDS need to be matched back with clinical conditions that are experienced by the person examined.

An examination of the actual LED can be one of the tests in the diagnosis of diseases such as enforcing temporal arteritis which happens very extreme enhancement from LED (> 100 mm/hour). This disease is one of the great inflammatory disease in which the sufferer may complain of headaches, impaired vision and pain in the face. In addition the inspection LED to date is still the option to assess the progression of the disease such as temporal arteritis, inflammatory arthritis is also a number of infections and the response was against the therapy.

Thus a number of conditions which are often suspected to be the cause of high blood creep rate of laboratory examination results. As we have discussed earlier, the examination is not actually LED to a specific examination to a LED outcomes condition so that high should remain associated with the clinical condition of the complaints and also the results of the physical examination someone. Therefore, if you see your blood workup and found an increase LED do not panic! Checking yourself to your doctor and ask for an explanation of the words, the end of this article may be of benefit to us all.

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